AP2S1
Sign in to saveAlso known as AP17, CLAPS2, FBH3, FBHOk, HHC3, adaptor related protein complex 2 sigma 1 subunit, adaptor related protein complex 2 subunit sigma 1
AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.
In the Vinony graph
Vinony's link graph records 82 inbound references to AP2S1, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 6 Wikipedia language editions.
Gene data
AP2S1- Name
- adaptor related protein complex 2 subunit sigma 1
- Type
- protein-coding
- Position
- 46,838,136–46,850,962 (−)
- Aliases
- AP17, CLAPS2, FBH3, FBHOk, HHC3
- Ensembl
- ENSG00000042753
- RefSeq RNA
- NM_001301076.3, NM_001301078.3, NM_001301081.3, NM_004069.6, NM_021575.5
- RefSeq protein
- NP_001288005.1, NP_001288007.1, NP_001288010.1, NP_004060.2, NP_067586.1
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
adaptor related protein complex 2 subunit sigma 1
- Symbol
- AP2S1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:46,838,136-46,850,962
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 2VGL AP-2 complex subunit sigma within the AP2 CLATHRIN ADAPTOR CORE.png
Show 8 more facts
- HomoloGene ID
- 3001
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1175
- genomic end
- 46850846
- genomic start
- 47341393
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.32
- expressed in
- cingulate gyrus
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.
Excerpted from Wikipedia’s “AP2S1” article, available under the CC BY-SA 4.0 licence.