AP2S1

Also known as AP17, CLAPS2, FBH3, FBHOk, HHC3, adaptor related protein complex 2 sigma 1 subunit, adaptor related protein complex 2 subunit sigma 1

AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.

Gene data

AP2S1

Name: adaptor related protein complex 2 subunit sigma 1
Type: protein-coding
Position: 46,838,136–46,850,882 (−)
Aliases: AP17, CLAPS2, FBH3, FBHOk, HHC3
Ensembl: ENSG00000042753
RefSeq RNA: NM_001301076.3, NM_001301078.3, NM_001301081.3, NM_004069.6, NM_021575.5
RefSeq protein: NP_001288005.1, NP_001288007.1, NP_001288010.1, NP_004060.2, NP_067586.1

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].

Gene Ontology

Biological process

intracellular protein transport protein transport

Article

3 sections

Contents

References
Further reading
External links

AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.