aranidipine

Aranidipine (INN, trade name Sapresta) is a calcium channel blocker. It is a dihydropyridine derivative with two active metabolites (M-1α and M-1β). It was developed by Maruko Seiyaku and has the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. Its main use is as a hypotensive, reducing blood pressure.

In the Vinony graph

Vinony's link graph records 322 inbound references to aranidipine, and connects out to valproic acid, (RS)-baclofen and voltage-gated sodium channel.

It sits within the topics 2-Nitrophenyl compounds, Calcium channel blockers and Carboxylate esters.

Vinony links it to 6 Wikipedia language editions.

Chemical data

Formula: C19H20N2O7
Molecular weight: 388.4 g/mol
IUPAC name: 3-O-methyl 5-O-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCC(=O)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
InChIKey: NCUCGYYHUFIYNU-UHFFFAOYSA-N
XLogP: 2
Polar surface area: 128 Å²
H-bond donors: 1
H-bond acceptors: 8
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 388.127051
Has use: medication

Show 3 more facts

chemical formula: C₁₉H₂₀N₂O₇
canonical SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCC(=O)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
Commons category: Aranidipine

Sources (2)

via Wikidata · CC0

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