riodipine

Chemical data

Formula

C18H19F2NO5

Molecular weight

367.3 g/mol

IUPAC name

dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

SMILES

CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2OC(F)F)C(=O)OC

InChIKey

AZVFIZVKGSPGPK-UHFFFAOYSA-N

XLogP

3.3

Polar surface area

73.9 Ų

H-bond donors

1

H-bond acceptors

8

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• [Effects of nifedipine and riodipine on biochemical processes in intact erythrocytes].Biulleten' eksperimental'noi biologii i meditsiny · 1990
• [The antiepileptic effects of sodium valproate and the calcium antagonist riodipine when used jointly in a model of focal penicillin-induced epileptic activity].Biulleten' eksperimental'noi biologii i meditsiny · 1992
• [The anticonvulsive activity of the 1,4-dihydropyridine derivative riodipine and other anticonvulsants when used in combination].Biulleten' eksperimental'noi biologii i meditsiny · 1993
• [Effect of the calcium antagonists ryodipine and verapamil on the carnitine-dependent metabolism of fatty acids in the rat heart].Farmakologiia i toksikologiia · 1989
• [The antiepileptic effects of sodium valproate and the calcium antagonist riodipine when used jointly in a model of generalized korazol-induced epileptic activity].Biulleten' eksperimental'noi biologii i meditsiny · 1992

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

367.123

via Wikidata · CC0