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butaperazine

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Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class. It was approved in 1967, and possibly discontinued in the 1980s.

Wikidata facts

Mass
409.219
Show 4 more facts
defined daily dose
10
Commons category
Butaperazine
chemical formula
C₂₄H₃₁N₃OS
canonical SMILES
CCCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCN(CC4)C
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Encyclopedic overview

3 sections
Contents
  • Synthesis
  • See also
  • References

Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class. It was approved in 1967, and possibly discontinued in the 1980s.

==Synthesis== class=skin-invert-image|thumb|center|500px|Synthesis of butaperazine Butaperazine can be synthesized starting from 2-butyrylphenothiazine (1). It is prepared in a manner that is comparable to the method used in the synthesis of propiomazine and propiopromazine. The phenothiazine is alkylated with 1-(γ-chloropropyl)-4-methylpiperazine (2), which is prepared in the conventional way by alkylating 1-methylpiperazine with 1-bromo-3-chloropropane.

Excerpted from Wikipedia’s “butaperazine” article, available under the CC BY-SA 4.0 licence.

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