CACNB2
Sign in to saveAlso known as CACNLB2, CAVB2, MYSB, calcium voltage-gated channel auxiliary subunit beta 2, CAB2
Voltage-dependent L-type calcium channel subunit beta-2 is a protein that in humans is encoded by the CACNB2 gene.
Gene data
CACNB2- Name
- calcium voltage-gated channel auxiliary subunit beta 2
- Type
- protein-coding
- Aliases
- CAB2, CACNLB2, CAVB2, MYSB
This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013].
via MyGene.info
Gene · Ensembl
calcium voltage-gated channel auxiliary subunit beta 2
- Symbol
- CACNB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:18,140,322-18,543,557
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CACNB2 PDB 1t0h.png
Show 5 more facts
- HomoloGene ID
- 75191
- exact match
- identifiers.org/ncbigene/783
- genomic end
- 18543557
- genomic start
- 18140424
- cytogenetic location
- 10p12.33-p12.31
Sources (3)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Clinical significance
- See also
- References
- Further reading
- External links
Voltage-dependent L-type calcium channel subunit beta-2 is a protein that in humans is encoded by the CACNB2 gene.
== Clinical significance ==