Structure via PubChem · Public domain (PubChem)
کارپروفن
Sign in to saveAlso known as Ro-205720000, 6-chloro-alpha-methyl-9H-carbazole-2-acetic acid, (+-)-6-chloro-alpha-methylcarbazole-2-acetic acid, 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid, Carprofen, 6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid, Carprofène, (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid
thumb|100px|A 100 Kilogram#SI multiples|mg Rimadyl tablet approximately wide by thick, as sold in the USA.
Key facts
- Drug.PubChem
- 2581
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 460020416
- Drug.image
- Carprofen.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 280
- Drug.alt
- Two-dimensional monochrome diagram showing the structure of the molecule of Carprofen, uing the hexagonal style to depict a chemical compound.
- Drug.caption
- Carprofen molecule
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Rimadyl, others
- Drug.DailyMedID
- Carprofen
- Drug.routes_of_administration
- By mouth, injection
- Drug.ATCvet
- yes
- Drug.ATC_prefix
- M01
- Drug.ATC_suffix
- AE91
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.protein_bound
- High (99%)
via Wikipedia infobox
Chemical data
- Formula
- C15H12ClNO2
- Molecular weight
- 273.71 g/mol
- IUPAC name
- 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
- SMILES
- CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O
- InChIKey
- PUXBGTOOZJQSKH-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 53.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1987
- Admin. routes
- oral
via ChEMBL · EBI
Research
797 papers- Clinical evaluation of postoperative analgesia, cardiorespiratory parameters and changes in liver and renal function tests of paracetamol compared to meloxicam and carprofen in dogs undergoing ovariohysterectomy.PloS one · 2020
- Efficacy of meloxicam compared with carprofen for treating canine osteoarthritis.The Veterinary record · 2020
- Use of carprofen for the treatment of pain and inflammation in dogs.Journal of the American Veterinary Medical Association · 1997
- Pharmacokinetics and bioavailability of carprofen in sheep.Journal of veterinary pharmacology and therapeutics · 2022
- Carprofen: a new nonsteroidal antiinflammatory drug. Pharmacology, clinical efficacy and adverse effects.Pharmacotherapy · 1987
via PubMed
Wikidata facts
- Mass
- 273.056
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₅H₁₂ClNO₂
- canonical SMILES
- CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O
- World Health Organisation international non-proprietary name
- carprofen
- subject has role
- non-steroidal anti-inflammatory drug
- physically interacts with
- Prostaglandin-endoperoxide synthase 2
- Commons category
- Carprofen
via Wikidata · CC0