CDKN1C
Sign in to saveAlso known as BWCR, BWS, KIP2, WBS, p57, p57Kip2, cyclin-dependent kinase inhibitor 1C, cyclin dependent kinase inhibitor 1C
protein-coding gene in the species Homo sapiens
Gene data
CDKN1C- Name
- cyclin dependent kinase inhibitor 1C
- Type
- protein-coding
- Aliases
- BWCR, BWS, KIP2, WBS, p57, p57Kip2
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
via MyGene.info
Gene · Ensembl
cyclin dependent kinase inhibitor 1C
- Symbol
- CDKN1C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR11_1_CTG7:115,392-118,091
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 133549
- exact match
- identifiers.org/ncbigene/1028
- genomic start
- 2904443
- genomic end
- 2885775
- cytogenetic location
- 11p15.4
via Wikidata · CC0