CUL7
Sign in to saveAlso known as 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
Gene data
CUL7- Name
- cullin 7
- Type
- protein-coding
- Aliases
- 3M1, CUL-7, KIAA0076, dJ20C7.5
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
via MyGene.info
Gene · Ensembl
cullin 7
- Symbol
- CUL7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:43,037,617-43,053,943
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CUL7 PDB 2jng.png
Show 5 more facts
- HomoloGene ID
- 56683
- exact match
- identifiers.org/ncbigene/9820
- genomic end
- 43053943
- genomic start
- 43005355
- cytogenetic location
- 6p21.1
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Clinical significance
- Interactions
- References
- Further reading
- External links
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
== Clinical significance == It is associated with 3-M syndrome.
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