CHD3
Sign in to saveAlso known as Mi-2a, Mi2-ALPHA, ZFH, chromodomain helicase DNA binding protein 3, SNIBCPS
Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.
Gene data
CHD3- Name
- chromodomain helicase DNA binding protein 3
- Type
- protein-coding
- Aliases
- Mi-2a, Mi2-ALPHA, SNIBCPS, ZFH
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
chromodomain helicase DNA binding protein 3
- Symbol
- CHD3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:7,884,787-7,912,760
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 62693
- exact match
- identifiers.org/ncbigene/1107
- genomic end
- 7816078
- genomic start
- 7884796
- cytogenetic location
- 17p13.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.
== Function ==