dexetimide
Sign in to saveAlso known as (+)-benzetimide, R 16470, Tremblex®
Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.
Research
173 papers- PET Imaging of brain muscarinic receptors with (18)F-Fluorobenzyl-Dexetimide: A first in human study.Psychiatry research. Neuroimaging · 2021
- Human biodistribution and internal dosimetry of 4-[ (18)F]fluorobenzyl-dexetimide: a PET radiopharmaceutical for imaging muscarinic acetylcholine receptors in the brain and heart.EJNMMI research · 2020
- [Effect of dexetimide on intra-ocular pressure].Revista do Hospital das Clinicas · 1975
- Comparison of atropine and dexetimide in treatment of intoxications by selected organophosphates.Acta pharmacologica et toxicologica · 1982
- Dexetimide, a useful tool in acetylcholine-receptor localization.European journal of pharmacology · 1973
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Wikidata facts
- Mass
- 362.199428
Show 4 more facts
- chemical formula
- C₂₃H₂₆N₂O₂
- isomeric SMILES
- C1CN(CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
- canonical SMILES
- C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
- defined daily dose
- 0.125
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Article
1 sectionsContents
- References
Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.
== References ==
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