DRD4

Name

dopamine receptor D4

Type

protein-coding

Position

637,269–640,706 (+)

Aliases

D4DR

Ensembl

ENSG00000069696

RefSeq RNA

NM_000797.4

RefSeq protein

NP_000788.2

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

dopamine receptor D4

Symbol

DRD4

Biotype

Protein coding

Organism

Homo sapiens

Location

11:637,269-640,706

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0