Also known as CL100, HVH1, MKP-1, MKP1, PTPN10, dual specificity phosphatase 1
Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017].
Biological process
Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.
== Function ==
Molecular function
via MyGene.info
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).