E-6801
Sign in to saveAlso known as E 6801
E-6801 is a partial agonist of the 5-HT6 receptor. It enhanced recognition memory and reversed the memory deficits of scopolamine in an object recognition task in a rat model. The mechanism of memory enhancement is due to a combined modulation of cholinergic and glutamatergic neurotransmission.
Wikidata facts
- Mass
- 423.059045
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- chemical formula
- C₁₇H₁₈ClN₅O₂S₂
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)NS(=O)(=O)C3=C(N=C4N3C=CS4)Cl
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{{Chembox | ImageFile = E_6801.svg | ImageClass = skin-invert-image | ImageSize = | ImageAlt = | PIN = 6-Chloro-N-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}imidazo[2,1-b][1,3]thiazole-5-sulfonamide | OtherNames = |Section1= |Section2= |Section3= }}
E-6801 is a partial agonist of the 5-HT6 receptor. It enhanced recognition memory and reversed the memory deficits of scopolamine in an object recognition task in a rat model. The mechanism of memory enhancement is due to a combined modulation of cholinergic and glutamatergic neurotransmission.