EPHA1
Sign in to saveAlso known as 5730453L17Rik, AL033318, Eph, Esk, EPHT, EPHT1, EPH receptor A1
protein-coding gene in the species Homo sapiens
Gene data
EPHA1- Name
- EPH receptor A1
- Type
- protein-coding
- Position
- 143,390,289–143,408,880 (−)
- Aliases
- EPH, EPHT, EPHT1
- Ensembl
- ENSG00000146904
- RefSeq RNA
- NM_005232.5
- RefSeq protein
- NP_005223.4
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
EPH receptor A1
- Symbol
- EPHA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:143,390,289-143,408,880
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI