EPHA1

Also known as 5730453L17Rik, AL033318, Eph, Esk, EPHT, EPHT1, EPH receptor A1

protein-coding gene in the species Homo sapiens

Gene data

EPHA1

Name: EPH receptor A1
Type: protein-coding
Aliases: EPH, EPHT, EPHT1

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008].

via MyGene.info