AATK
Sign in to saveAlso known as AATYK, AATYK1, LMR1, LMTK1, PPP1R77, p35BP, apoptosis-associated tyrosine kinase, aatyk1
Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.
Gene data
AATK- Name
- apoptosis associated tyrosine kinase
- Type
- protein-coding
- Aliases
- AATYK, AATYK1, LMR1, LMTK1, PPP1R77, p35BP
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].
via MyGene.info
Gene · Ensembl
apoptosis associated tyrosine kinase
- Symbol
- AATK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,110,487-81,166,228
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 74861
- genomic end
- 79139877
- exact match
- identifiers.org/ncbigene/9625
- genomic start
- 81110487
- cytogenetic location
- 17q25.3
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Structure and expression
- Function
- References
- Further reading
- External links
Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.
==Structure and expression==