EPHB4

Name

EPH receptor B4

Type

protein-coding

Position

100,802,563–100,827,584 (−)

Aliases

CMAVM2, HFASD, HTK, LMPHM7, MYK1, TYRO11

Ensembl

ENSG00000196411

RefSeq RNA

NM_004444.5, XM_017011816.2, XM_054357461.1

RefSeq protein

NP_004435.3, XP_016867305.1, XP_054213436.1

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

EPH receptor B4

Symbol

EPHB4

Biotype

Protein coding

Organism

Homo sapiens

Location

7:100,802,563-100,827,584

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein EPHB4 PDB 2bba.png

via Wikidata · CC0