EPHB4

Name

EPH receptor B4

Type

protein-coding

Aliases

CMAVM2, HFASD, HTK, LMPHM7, MYK1, TYRO11

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

EPH receptor B4

Symbol

EPHB4

Biotype

Protein coding

Organism

Homo sapiens

Location

7:100,802,563-100,827,584

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein EPHB4 PDB 2bba.png

via Wikidata · CC0