Also known as BRK, protein tyrosine kinase 6
Tyrosine-protein kinase 6 is an enzyme that in humans is encoded by the PTK6 gene.
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
Biological process
Tyrosine-protein kinase 6 is an enzyme that in humans is encoded by the PTK6 gene.
== Function ==
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Molecular function
Cellular component
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).