GNAQ

Also known as CMC1, G-ALPHA-q, GAQ, SWS, G protein subunit alpha q

Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.

Gene data

GNAQ

Name: G protein subunit alpha q
Type: protein-coding
Position: 77,716,097–78,031,972 (−)
Aliases: CMAL, G-ALPHA-q, GAQ, SWS
Ensembl: ENSG00000156052
RefSeq RNA: NM_002072.5, XM_047423239.1, XM_047423240.1, XM_054362755.1, XM_054362756.1
RefSeq protein: NP_002063.2, XP_047279195.1, XP_047279196.1, XP_054218730.1, XP_054218731.1

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].

Gene Ontology

Biological process

signal transduction G protein-coupled receptor signaling pathway

~1 min read

Article

5 sections

Contents

Function
Interactions
See also
References
Further reading

Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.

== Function ==