GNAQ

Also known as CMC1, G-ALPHA-q, GAQ, SWS, G protein subunit alpha q

Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.

In the Vinony graph

Vinony's link graph records 310 inbound references to GNAQ, and connects out to Q180686, Online Mendelian Inheritance in Man and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 9.

Vinony links it to 6 Wikipedia language editions.

Gene data

GNAQ

Name: G protein subunit alpha q
Type: protein-coding
Position: 77,716,097–78,032,500 (−)
Aliases: CMAL, G-ALPHA-q, GAQ, SWS
Ensembl: ENSG00000156052
RefSeq RNA: NM_002072.5, XM_047423239.1, XM_047423240.1, XM_054362755.1, XM_054362756.1
RefSeq protein: NP_002063.2, XP_047279195.1, XP_047279196.1, XP_054218730.1, XP_054218731.1

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].

Pathways

Rap1 signaling pathway - Homo sapiens (human)Calcium signaling pathway - Homo sapiens (human)cGMP-PKG signaling pathway - Homo sapiens (human)Chemokine signaling pathway - Homo sapiens (human)Sphingolipid signaling pathway - Homo sapiens (human)Adrenergic signaling in cardiomyocytes - Homo sapiens (human)Vascular smooth muscle contraction - Homo sapiens (human)Apelin signaling pathway - Homo sapiens (human)Gap junction - Homo sapiens (human)Platelet activation - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

G protein subunit alpha q

Symbol: GNAQ
Biotype: Protein coding
Organism: Homo sapiens
Location: 9:77,716,097-78,032,500
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein GNAQ PDB 2bcj.png

Show 5 more facts

exact match: identifiers.org/ncbigene/2776
HomoloGene ID: 1566
genomic end: 78031811
genomic start: 77716097
cytogenetic location: 9q21.2

Sources (6)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections

Contents

Function
Interactions
See also
References
Further reading

Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.

== Function ==

Excerpted from Wikipedia’s “GNAQ” article, available under the CC BY-SA 4.0 licence.