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GeneQ18026795· pop 5· linked from 409 articles

Also known as hyaluronan synthase 3

Hyaluronan synthase 3 is an enzyme that in humans is encoded by the HAS3 gene.

In the Vinony graph

Vinony's link graph records 409 inbound references to HAS3, and connects out to glucuronosyltransferase, PubMed and hyaluronic acid.

It is catalogued under the topic Genes on human chromosome 16.

Vinony links it to 5 Wikipedia language editions.

Gene data

HAS3
Name
hyaluronan synthase 3
Type
protein-coding
Position
69,105,641–69,121,460 (+)
RefSeq RNA
NM_001199280.2, NM_005329.3, NM_138612.3, XM_005255921.3, XM_011523061.3
RefSeq protein
NP_001186209.1, NP_005320.2, NP_619515.1, XP_005255978.1, XP_011521363.1

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010].

via MyGene.info

Gene · Ensembl

hyaluronan synthase 3

Symbol
HAS3
Biotype
Protein coding
Organism
Homo sapiens
Location
16:69,105,641-69,121,460
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
68461
found in taxon
Homo sapiens
genomic end
69152622
genomic start
69105653
cytogenetic location
16q22.1
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Hyaluronan synthase 3 is an enzyme that in humans is encoded by the HAS3 gene.

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Two transcript variants encoding different isoforms have been found for this gene.

Excerpted from Wikipedia’s “HAS3” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

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