Structure via PubChem · Public domain (PubChem)
ibopamine
Sign in to saveIbopamine is a sympathomimetic drug, designed as a prodrug of epinine (deoxyepinephrine or N-methyldopamine), used in ophthalmology. It induces mydriasis. It also has been investigated for use in the treatment of congestive heart failure.
Chemical data
- Formula
- C17H25NO4
- Molecular weight
- 307.4 g/mol
- IUPAC name
- [4-[2-(methylamino)ethyl]-2-(2-methylpropanoyloxy)phenyl] 2-methylpropanoate
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
359 papers- Ibopamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in congestive heart failure.Drugs & aging · 1993
- Clinical pharmacology of ibopamine.The American journal of medicine · 1991
- Neurohormonal and hemodynamic effects of ibopamine.Clinical cardiology · 1995
- Ibopamine. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.Drugs · 1988
- [Ibopamine--clinical results].Zeitschrift fur Kardiologie · 1991
via PubMed
Wikidata facts
- Mass
- 307.178
Show 2 more facts
- chemical formula
- C₁₇H₂₅NO₄
- canonical SMILES
- CC(C)C(=O)OC1=C(C=C(C=C1)CCNC)OC(=O)C(C)C
Sources (2)
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Pharmacokinetics
- Pharmacodynamics
- Toxicology
- Clinical Use
- See also
- References
Ibopamine is a sympathomimetic drug, designed as a prodrug of epinine (deoxyepinephrine or N-methyldopamine), used in ophthalmology. It induces mydriasis. It also has been investigated for use in the treatment of congestive heart failure.
It acts on D1 and α-adrenergic receptors as an agonist.
Connections
adrenergic receptor
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propranolol
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sympathomimetic drug
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atenolol
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labetalol
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levobunolol
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deoxyepinephrine
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exaprolol
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digital object identifier
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chemical formula
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ophthalmology
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epinephrine
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heart failure
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dopamine
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lysergic acid diethylamide
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molar mass
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(RS)-ketamine
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Q180686
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atropine
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phenylalanine
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Categories
Alpha1-adrenergic agonistsAlpha2-adrenergic agonistsBeta-adrenergic agonistsChemical pages without DrugBank identifierD1 receptor agonistsD2 receptor agonistsDopamine agonistsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with no legal statusECHA InfoCard ID from WikidataIsobutyrate estersMethoxyphenethylaminesOphthalmology drugsProdrugs