indobufen

Chemical data

Formula

C18H17NO3

Molecular weight

295.3 g/mol

IUPAC name

2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid

SMILES

CCC(C1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O)C(=O)O

InChIKey

AYDXAULLCROVIT-UHFFFAOYSA-N

XLogP

3.1

Polar surface area

57.6 Ų

H-bond donors

1

H-bond acceptors

3

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 3

Molecule type

Small molecule

Indications

Recurrent thrombophlebitis, atrial fibrillation

via ChEMBL · EBI

• Indobufen or Aspirin on Top of Clopidogrel After Coronary Drug-Eluting Stent Implantation (OPTION): A Randomized, Open-Label, End Point-Blinded, Noninferiority Trial.Circulation · 2023
• Indobufen versus aspirin in patients with indication for antiplatelet therapy: A systematic review and meta-analysis.Vascular pharmacology · 2025
• Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial.The Lancet. Neurology · 2023
• Indobufen versus aspirin after percutaneous coronary intervention in elderly patients with acute coronary syndrome.BMC cardiovascular disorders · 2025
• Indobufen: an updated review of its use in the management of atherothrombosis.Drugs & aging · 2001

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

295.121

Has use

medication

via Wikidata · CC0