Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, لیکوفلون is referenced by 215 other articles, and connects out to prostaglandin-endoperoxide synthase, clonixin and selenium.
It sits within the topics Abandoned drugs, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C23H22ClNO2
- Molecular weight
- 379.9 g/mol
- IUPAC name
- 2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid
- SMILES
- CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C
- InChIKey
- UAWXGRJVZSAUSZ-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 42.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
157 papers- Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders.Prostaglandins & other lipid mediators · 2021
- Licofelone--clinical update on a novel LOX/COX inhibitor for the treatment of osteoarthritis.Rheumatology (Oxford, England) · 2004
- Licofelone--a novel analgesic and anti-inflammatory agent.Current topics in medicinal chemistry · 2007
- Poly-beta-amino-ester licofelone conjugates development for osteoarthritis treatment.RSC advances · 2024
- Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators.Inflammation · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 379.13390662399996
Show 3 more facts
- chemical formula
- C₂₃H₂₂ClNO₂
- canonical SMILES
- CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C
- Commons category
- Licofelone
Sources (2)
via Wikidata · CC0
Connections
prostaglandin-endoperoxide synthase
Entity
clonixin
Entity
selenium
Entity
enzyme
Entity
aspirin
Entity
digital object identifier
Entity
Paracetamol
Concept
chemical formula
Entity
ibuprofen
Entity
molar mass
Entity
osteoarthritis
Entity
PubMed
Entity
salicylic acid
Entity
CAS Registry Number
Entity
Diclofenac
Entity
non-steroidal anti-inflammatory drug
Entity
PubMed Central
Entity
PubChem
Entity
signaling receptor
Entity
naproxen
Entity