Structure via PubChem · Public domain (PubChem)
lornoxicam
Sign in to saveAlso known as Ro-139297, chlortenoxicam, Xefocam, Acabel, Telos, Lorcam, CLTX, Safem
Lornoxicam, also known as chlortenoxicam, is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.
In the Vinony graph
Vinony's link graph records 490 inbound references to lornoxicam, and connects out to salicylic acid, metamizole sodium and route of administration.
It is catalogued under topics including 2-Pyridyl compounds, Carboxamides and Chloroarenes.
Vinony links it to 17 Wikipedia language editions.
Chemical data
- Formula
- C13H10ClN3O4S2
- Molecular weight
- 371.8 g/mol
- IUPAC name
- 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
- SMILES
- CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3
- InChIKey
- WLHQHAUOOXYABV-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 136 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- rheumatic disease, pain, Alzheimer disease, migraine disorder
via ChEMBL · EBI
Research
482 papers- Lornoxicam.2006
- Lornoxicam.Profiles of drug substances, excipients, and related methodology · 2011
- Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions.Drugs · 1996
- Clinical pharmacokinetics of lornoxicam. A short half-life oxicam.Clinical pharmacokinetics · 1998
- Clinical pharmacokinetic studies with lornoxicam.Postgraduate medical journal · 1990
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- sulfur
- Mass
- 370.980125
- Has use
- medication
Show 6 more facts
- Commons category
- Lornoxicam
- subject has role
- non-steroidal anti-inflammatory drug
- chemical formula
- C₁₃H₁₀ClN₃O₄S₂
- canonical SMILES
- CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3
- World Health Organisation international non-proprietary name
- lornoxicam
- defined daily dose
- 12
Sources (6)
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Interactions
- See also
- References
Lornoxicam, also known as chlortenoxicam, is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.
It was patented in 1977 and approved for medical use in 1997. Brand names include Xefo and Xefocam among others.
Excerpted from Wikipedia’s “lornoxicam” article, available under the CC BY-SA 4.0 licence.