MARK2
Sign in to saveAlso known as EMK-1, EMK1, PAR-1, Par-1b, Par1b, microtubule affinity regulating kinase 2
Gen der Spezies Homo sapiens
Gene data
MARK2- Name
- microtubule affinity regulating kinase 2
- Type
- protein-coding
- Position
- 63,838,852–63,911,020 (+)
- Aliases
- EMK-1, EMK1, MRD76, PAR-1, Par-1b, Par1b
- Ensembl
- ENSG00000072518
- RefSeq RNA
- NM_001039469.3, NM_001163296.2, NM_001163297.2, NM_004954.5, NM_017490.4
- RefSeq protein
- NP_001034558.2, NP_001156768.1, NP_001156769.1, NP_004945.4, NP_059672.2
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
microtubule affinity regulating kinase 2
- Symbol
- MARK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:63,838,852-63,911,020
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein MARK2 PDB 1y8g.png
Show 7 more facts
- HomoloGene ID
- 69013
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2011
- genomic end
- 63911020
- genomic start
- 63606400
- chromosome
- human chromosome 11
- cytogenetic location
- 11q13.1
Sources (3)
via Wikidata · CC0