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meglutol

Structure via PubChem · Public domain (PubChem)

EntityQ524670· pop 8· linked from 95 articles

Also known as beta-hydroxy-beta-methylglutaric acid, 3-hydroxy-3-methyl-glutaric acid, 3-hydroxy-3-methyl-pentanedioic acid, 3-Hydroxy-3-methylglutaric acid, 3-Hydroxy-3-methylglutarate, 3-Methyl-3-hydroxyglutarate, b-Hydroxy-b-methylglutarate, Dicrotalate

Meglutol (INN, also known as 3-hydroxy-3-methylglutaric acid, β-hydroxy-β-methylglutaric acid, and dicrotalic acid) is a hypolipidemic agent.

In the Vinony graph

Vinony's link graph records 95 inbound references to meglutol, and connects out to liver, medication and circulatory system.

Vinony files it under Aldols, Dicarboxylic acids and Drugboxes which contain changes to verified fields.

Vinony links it to 8 Wikipedia language editions.

Chemical data

Formula
C6H10O5
Molecular weight
162.14 g/mol
IUPAC name
3-hydroxy-3-methylpentanedioic acid
SMILES
CC(CC(=O)O)(CC(=O)O)O
InChIKey
NPOAOTPXWNWTSH-UHFFFAOYSA-N
XLogP
-1.2
Polar surface area
94.8 Ų
H-bond donors
3
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
cardiovascular disease

via ChEMBL · EBI

Research

148 papers

via PubMed

Wikidata facts

Subclass of
fatty acid
Mass
162.053
Show 4 more facts
chemical formula
C₆H₁₀O₅
canonical SMILES
CC(CC(=O)O)(CC(=O)O)O
World Health Organisation international non-proprietary name
meglutol
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • See also

Meglutol (INN, also known as 3-hydroxy-3-methylglutaric acid, β-hydroxy-β-methylglutaric acid, and dicrotalic acid) is a hypolipidemic agent.

It occurs free in Crotalaria dura and C. globifera and is bound in dicrotaline (pyrrolizidine alkaloid).

Excerpted from Wikipedia’s “meglutol” article, available under the CC BY-SA 4.0 licence.

Available in 8 languages

via Wikidata sitelinks · CC0

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