Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Vinony's link graph records 273 inbound references to ニムスチン, and connects out to tiazofurin, medication and digital object identifier.
Vinony files it under Alkylating antineoplastic agents, Chemical pages without DrugBank identifier and Chloroethyl compounds.
Vinony links it to 8 Wikipedia language editions.
Chemical data
- Formula
- C9H13ClN6O2
- Molecular weight
- 272.69 g/mol
- IUPAC name
- 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea
- SMILES
- CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O
- InChIKey
- VFEDRRNHLBGPNN-UHFFFAOYSA-N
- XLogP
- 0.4
- Polar surface area
- 114 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- neoplasm, glioblastoma multiforme
via ChEMBL · EBI
Research
951 papers- Therapeutic effect of nimustine in a dog with intracranial histiocytic sarcoma.Open veterinary journal · 2024
- Nimustine Treatment of 11 Cases of Canine Histiocytic Sarcoma.Journal of the American Animal Hospital Association · 2020
- Retrospective evaluation of nimustine use in the treatment of feline lymphoma.Veterinary medicine and science · 2022
- Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study.The Tohoku journal of experimental medicine · 2023
- Regression of Recurrent Spinal Cord High-Grade Glioma After Convection-Enhanced Delivery of Nimustine Hydrochloride: Case Reports and Literature Review.Operative neurosurgery (Hagerstown, Md.) · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 272.078851
- Has use
- medication
Show 4 more facts
- chemical formula
- C₉H₁₃ClN₆O₂
- canonical SMILES
- CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O
- Commons category
- Nimustine
- subject has role
- antineoplastic
Sources (2)
via Wikidata · CC0
Article · 日本語
ニムスチン（英語: Nimustine、略称:ACNU）は、ニトロソウレア系のアルキル化剤である。悪性腫瘍の治療に用いられる。製品名はニドラン（第一三共が製造販売）。
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 8 languages
via Wikidata sitelinks · CC0
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