Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, 尼莫司汀 is referenced by 273 other articles, and connects out to tiazofurin, medication and digital object identifier.
Vinony files it under Alkylating antineoplastic agents, Chemical pages without DrugBank identifier and Chloroethyl compounds.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C9H13ClN6O2
- Molecular weight
- 272.69 g/mol
- IUPAC name
- 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea
- SMILES
- CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O
- InChIKey
- VFEDRRNHLBGPNN-UHFFFAOYSA-N
- XLogP
- 0.4
- Polar surface area
- 114 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- neoplasm, glioblastoma multiforme
via ChEMBL · EBI
Research
951 papers- Therapeutic effect of nimustine in a dog with intracranial histiocytic sarcoma.Open veterinary journal · 2024
- Nimustine Treatment of 11 Cases of Canine Histiocytic Sarcoma.Journal of the American Animal Hospital Association · 2020
- Retrospective evaluation of nimustine use in the treatment of feline lymphoma.Veterinary medicine and science · 2022
- Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study.The Tohoku journal of experimental medicine · 2023
- Regression of Recurrent Spinal Cord High-Grade Glioma After Convection-Enhanced Delivery of Nimustine Hydrochloride: Case Reports and Literature Review.Operative neurosurgery (Hagerstown, Md.) · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 272.078851
- Has use
- medication
Show 4 more facts
- chemical formula
- C₉H₁₃ClN₆O₂
- canonical SMILES
- CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O
- Commons category
- Nimustine
- subject has role
- antineoplastic
Sources (2)
via Wikidata · CC0
Available in 8 languages
via Wikidata sitelinks · CC0
Connections
tiazofurin
Entity
medication
Entity
digital object identifier
Entity
chemical formula
Entity
chemotherapy
Entity
molar mass
Entity
PubMed
Entity
DNA replication
Entity
hydrazine
Entity
cell cycle
Entity
DL-asparagine
Entity
CAS Registry Number
Entity
PubChem
Entity
Anatomical Therapeutic Chemical Classification System
Entity
microtubule
Entity
gene therapy
Entity
arsenic trioxide
Entity
sex steroid
Entity
intravenous infusion and defusion
Entity
World Health Organization Model List of Essential Medicines
Entity