Structure via PubChem · Public domain (PubChem)
oxiracetam
Sign in to saveOxiracetam (developmental code name ISF 2522) is a nootropic drug of the racetam family and a very mild stimulant. Several studies suggest that the substance is safe even when high doses are consumed for a long period of time. However, the mechanism of action of the racetam drug family is still a matter of research. Oxiracetam is not approved by Food and Drug Administration for any medical use in the United States.
In the Vinony graph
Vinony's link graph records 865 inbound references to oxiracetam, and connects out to Anatomical Therapeutic Chemical Classification System, pentamidine and 1-aminocyclopropanecarboxylic acid.
It sits within the topics Acetamides, AMPA receptor positive allosteric modulators and Chemical pages without DrugBank identifier.
Vinony links it to 13 Wikipedia language editions.
Chemical data
- Formula
- C6H10N2O3
- Molecular weight
- 158.16 g/mol
- IUPAC name
- 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
- SMILES
- C1C(CN(C1=O)CC(=O)N)O
- InChIKey
- IHLAQQPQKRMGSS-UHFFFAOYSA-N
- XLogP
- -2.2
- Polar surface area
- 83.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- attention deficit hyperactivity disorder
via ChEMBL · EBI
Research
220 papers- Oxiracetam alleviates anti-inflammatory activity and ameliorates cognitive impairment in the early phase of traumatic brain injury.Acta neurochirurgica · 2023
- Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3 clinical trial.Signal transduction and targeted therapy · 2025
- [Oxiracetam].Giornale di clinica medica · 1989
- Oxiracetam and physical activity in preventing cognitive decline after stroke: A multicenter, randomized controlled trial.European stroke journal · 2025
- Co-administration of Nanowired Oxiracetam and Neprilysin with Monoclonal Antibodies to Amyloid Beta Peptide and p-Tau Thwarted Exacerbation of Brain Pathology in Concussive Head Injury at Hot Environment.Advances in neurobiology · 2023
via PubMed
Wikidata facts
- Subclass of
- secondary alcohol
- Mass
- 158.069
Show 4 more facts
- chemical formula
- C₆H₁₀N₂O₃
- canonical SMILES
- C1C(CN(C1=O)CC(=O)N)O
- subject has role
- nootropic
- Commons category
- Oxiracetam
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Clinical findings
- Pharmacokinetics
- References
- Further reading
- External links
Oxiracetam (developmental code name ISF 2522) is a nootropic drug of the racetam family and a very mild stimulant. Several studies suggest that the substance is safe even when high doses are consumed for a long period of time. However, the mechanism of action of the racetam drug family is still a matter of research. Oxiracetam is not approved by Food and Drug Administration for any medical use in the United States.
==Clinical findings== Oxiracetam has been studied to determine if it has an effect on symptoms of dementia, but no consistent results were obtained in patients with Alzheimer's dementia or organic solvent abuse.
Excerpted from Wikipedia’s “oxiracetam” article, available under the CC BY-SA 4.0 licence.