procainamida

Also known as Procan®, Pronestyl®, p-Aminobenzoic diethylaminoethylamide, p-Amino-N-(2-diethylaminoethyl)benzamide, Biocoryl, Procainamidum, Procainamide

composto químico

In the Vinony graph

Vinony's link graph records 399 inbound references to procainamida, and connects out to heart arrhythmia, antiarrhythmic agent and atropine.

It is catalogued under topics including 4-Aminophenyl compounds, Antiarrhythmic agents and Benzamides.

Vinony links it to 25 Wikipedia language editions.

Chemical data

Formula: C13H21N3O
Molecular weight: 235.33 g/mol
IUPAC name: 4-amino-N-[2-(diethylamino)ethyl]benzamide
SMILES: CCN(CC)CCNC(=O)C1=CC=C(C=C1)N
InChIKey: REQCZEXYDRLIBE-UHFFFAOYSA-N
XLogP: 0.9
Polar surface area: 58.4 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1950
Admin. routes: oral, parenteral
Indications: atrial fibrillation, heart failure, cardiac arrhythmia, myocardial infarction

via ChEMBL · EBI

Research

4,566 papers

Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study.European heart journal · 2017
Procainamide and disopyramide.European heart journal · 1987
Procainamide pharmacokinetics during extracorporeal membrane oxygenation.Perfusion · 2023
[Procainamide].Nihon rinsho. Japanese journal of clinical medicine · 1995
Procainamide-induced psychosis.Critical care nurse · 1993

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 235.168462
Has use: medication

Show 7 more facts

significant drug interaction: thioridazine
chemical formula: C₁₃H₂₁N₃O
medical condition treated: supraventricular tachycardia
canonical SMILES: CCN(CC)CCNC(=O)C1=CC=C(C=C1)N
World Health Organisation international non-proprietary name: procainamide
Commons category: Procainamide
has characteristic: bitterness

Sources (3)

via Wikidata · CC0

Article · Português

A procainamida é um fármaco do grupo dos antiarrítmicos da classe I, que é usado no tratamento da arritmia cardíaca. Menos efeitos antimuscarínicos que com quinidina.

Abstract from DBpedia / Wikipedia · CC BY-SA