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GeneQ18035610· pop 5· linked from 506 articles

Also known as retinal pigment epithelium-derived rhodopsin homolog

Peropsin, a visual pigment-like receptor, is a protein that in humans is encoded by the RRH gene. It belongs like other animal opsins to the G protein-coupled receptors. Even so, the first peropsins were already discovered in mice and humans in 1997, not much is known about them.

Gene data

RRH
Name
retinal pigment epithelium-derived rhodopsin homolog
Type
protein-coding

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

retinal pigment epithelium-derived rhodopsin homolog

Symbol
RRH
Biotype
Protein coding
Organism
Homo sapiens
Location
4:109,827,972-109,849,123
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
55977
genomic start
110749150
cytogenetic location
4q25
genomic end
109849123
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~4 min read

Article

6 sections
Contents
  • Photochemistry
  • Tissue localization
  • Gene localization and structure
  • Phylogeny
  • Clinical significance
  • References

Peropsin, a visual pigment-like receptor, is a protein that in humans is encoded by the RRH gene. It belongs like other animal opsins to the G protein-coupled receptors. Even so, the first peropsins were already discovered in mice and humans in 1997, not much is known about them.

== Photochemistry == Like most opsins, peropsins have in its seventh transmembrane domain a lysine corresponding to amino acid position 296 in cattle rhodopsin, which is important for retinal binding and light sensing.

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