SART3
Sign in to saveAlso known as DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb), squamous cell carcinoma antigen recognized by T-cells 3, squamous cell carcinoma antigen recognized by T cells 3
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the SART3 gene.
In the Vinony graph
Vinony's link graph records 10 inbound references to SART3, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 12 and Spliceosome.
Vinony links it to 7 Wikipedia language editions.
Gene data
SART3- Name
- spliceosome associated factor 3, U4/U6 recycling protein
- Type
- protein-coding
- Position
- 108,522,214–108,561,400 (−)
- Aliases
- DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb)
- Ensembl
- ENSG00000075856
- RefSeq RNA
- NM_001410983.1, NM_014706.4, XM_047429916.1, XM_054373894.1
- RefSeq protein
- NP_001397912.1, NP_055521.1, XP_047285872.1, XP_054229869.1
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
spliceosome associated factor 3, U4/U6 recycling protein
- Symbol
- SART3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:108,522,214-108,561,400
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SART3 PDB 2do4.png
Show 7 more facts
- HomoloGene ID
- 40977
- genomic end
- 108561400
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9733
- genomic start
- 108522214
- chromosome
- human chromosome 12
- cytogenetic location
- 12q23.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the SART3 gene.
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
Excerpted from Wikipedia’s “SART3” article, available under the CC BY-SA 4.0 licence.