CD3G
Sign in to saveAlso known as CD3-GAMMA, IMD17, T3G, CD3g molecule, CD3GAMMA, CD3 gamma subunit of T-cell receptor complex
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
In the Vinony graph
Vinony's link graph records 389 inbound references to CD3G, and connects out to PubMed, Ensembl genome database project and CD1.
It sits within the topics Clusters of differentiation and Genes on human chromosome 11.
Vinony links it to 5 Wikipedia language editions.
Gene data
CD3G- Name
- CD3 gamma subunit of T-cell receptor complex
- Type
- protein-coding
- Position
- 118,344,338–118,355,161 (+)
- Aliases
- CD3-GAMMA, CD3GAMMA, IMD17, T3G
- Ensembl
- ENSG00000160654
- RefSeq RNA
- NM_000073.3, NM_001440319.1, XM_005271724.5
- RefSeq protein
- NP_000064.1, NP_001427248.1, XP_005271781.1
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CD3 gamma subunit of T-cell receptor complex
- Symbol
- CD3G
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:118,344,338-118,355,161
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 55
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/917
- genomic end
- 118225876
- genomic start
- 118215059
- chromosome
- human chromosome 11
- cytogenetic location
- 11q23.3
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.
Excerpted from Wikipedia’s “CD3G” article, available under the CC BY-SA 4.0 licence.