CD3G
Sign in to saveAlso known as CD3-GAMMA, IMD17, T3G, CD3g molecule, CD3GAMMA, CD3 gamma subunit of T-cell receptor complex
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
Gene data
CD3G- Name
- CD3 gamma subunit of T-cell receptor complex
- Type
- protein-coding
- Aliases
- CD3-GAMMA, CD3GAMMA, IMD17, T3G
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
CD3 gamma subunit of T-cell receptor complex
- Symbol
- CD3G
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:118,344,338-118,355,161
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55
- exact match
- identifiers.org/ncbigene/917
- genomic end
- 118225876
- genomic start
- 118215059
- cytogenetic location
- 11q23.3
Sources (6)
via Wikidata · CC0
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4 sectionsContents
- See also
- References
- Further reading
- External links
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.