Also known as CD3-GAMMA, IMD17, T3G, CD3g molecule, CD3GAMMA, CD3 gamma subunit of T-cell receptor complex
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008].
via MyGene.info
T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.
T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.
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