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GeneQ18030077· pop 5· linked from 816 articles

Also known as NFAT4, NFATX, nuclear factor of activated T-cells 3, nuclear factor of activated T cells 3, NF-AT4c

Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.

Gene data

NFATC3
Name
nuclear factor of activated T cells 3
Type
protein-coding
Position
68,084,751–68,229,259 (+)
Aliases
NF-AT4c, NFAT4, NFATX, n339260
RefSeq RNA
NM_004555.4, NM_173163.3, NM_173164.1, NM_173165.3
RefSeq protein
NP_004546.1, NP_775186.1, NP_775188.1

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010].

via MyGene.info

Gene · Ensembl

nuclear factor of activated T cells 3

Symbol
NFATC3
Biotype
Protein coding
Organism
Homo sapiens
Location
16:68,084,751-68,229,259
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
27827
found in taxon
Homo sapiens
genomic end
68263162
genomic start
68118654
cytogenetic location
16q22.1
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • See also
  • References
  • Further reading
  • External links

Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene.

== Function ==

Excerpted from Wikipedia’s “NFATC3” article, available under the CC BY-SA 4.0 licence.

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