SDC1

Name

syndecan 1

Type

protein-coding

Position

20,200,796–20,225,433 (−)

Aliases

CD138, SDC, SYND1, syndecan

Ensembl

ENSG00000115884

RefSeq RNA

NM_001006946.2, NM_002997.5, XM_005262620.5, XM_005262621.3, XM_005262622.3

RefSeq protein

NP_001006947.2, NP_002988.4, XP_005262677.1, XP_005262678.3, XP_005262679.1

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

syndecan 1

Symbol

SDC1

Biotype

Protein coding

Organism

Homo sapiens

Location

2:20,200,796-20,225,512

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0