sertindole

Also known as sertindol, 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl}ethyl)imidazolidin-2-one

Sertindole, sold under the brand name Serdolect among others, is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company Lundbeck and marketed under license by Abbott Labs. Like other atypical antipsychotics, it has activity at dopamine and serotonin receptors in the brain. It is used in the treatment of schizophrenia.

Key facts

Drug.ChemSpiderID: 54229
Drug.Watchedfields: changed
Drug.verifiedrevid: 464389408
Drug.image: Sertindole.svg
Drug.image_class: skin-invert-image
Drug.width: 225px
Drug.image2: Sertindole ball-and-stick model.png
Drug.image_class2: bg-transparent
Drug.width2: 250px
Drug.tradename: Serdolect, others
Drug.pregnancy_AU: C
Drug.routes_of_administration: Oral
Drug.class: Atypical antipsychotic
Drug.ATC_prefix: N05
Drug.ATC_suffix: AE03
Drug.legal_AU: S4
Drug.legal_status: Rx-only
Drug.bioavailability: 75%

via Wikipedia infobox

Research

517 papers

Sertindole for schizophrenia.The Cochrane database of systematic reviews · 2005
Sertindole for the treatment of schizophrenia.Expert opinion on pharmacotherapy · 2010
Sertindole for schizophrenia.The Cochrane database of systematic reviews · 2000
Sertindole in schizophrenia: efficacy and safety issues.Expert opinion on pharmacotherapy · 2014
Sertindole: efficacy and safety in schizophrenia.Expert opinion on pharmacotherapy · 2006

via PubMed

Wikidata facts

Mass: 440.177917

Show 5 more facts

defined daily dose: 16
chemical formula: C₂₄H₂₆ClFN₄O
canonical SMILES: C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O
World Health Organisation international non-proprietary name: sertindole
Commons category: Sertindole

Sources (4)

via Wikidata · CC0

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