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SIB-1553A

Structure via PubChem · Public domain (PubChem)

EntityQ7390266· pop 5· linked from 776 articles

Also known as 4-[2-(1-methyl-2-pyrrolidinyl)ethylthio]phenol

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.

In the Vinony graph

Vinony's link graph records 776 inbound references to SIB-1553A, and connects out to agonist, nicotinic acetylcholine receptor and allosteric modulator.

Vinony files it under 4-Hydroxyphenyl compounds, Chembox image size set and Nicotinic agonists.

Vinony links it to 4 Wikipedia language editions.

Chemical data

Formula
C13H19NOS
Molecular weight
237.36 g/mol
IUPAC name
4-[2-(1-methylpyrrolidin-2-yl)ethylsulfanyl]phenol
SMILES
CN1CCCC1CCSC2=CC=C(C=C2)O
InChIKey
NVZGJSVPOOILDI-UHFFFAOYSA-N
XLogP
3
Polar surface area
48.8 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
237.119
Show 4 more facts
canonical SMILES
CN1CCCC1CCSC2=CC=C(C=C2)O
chemical formula
C₁₃H₁₉NOS
Commons category
SIB-1553A
subject has role
nootropic
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

{{Chembox | ImageFile = SIB-1553A.svg | ImageClass = skin-invert-image | ImageSize = 200px | ImageAlt = | PIN = 4-{[2-(1-Methylpyrrolidin-2-yl)ethyl]sulfanyl}phenol | OtherNames = |Section1= |Section2= |Section3= }}

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.

Excerpted from Wikipedia’s “SIB-1553A” article, available under the CC BY-SA 4.0 licence.

Available in 4 languages

via Wikidata sitelinks · CC0

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