English

English Deutsch Español Français Italiano Nederlands Português Svenska العربية

GeneQ18031656· pop 5· linked from 823 articles

SOX11

Sign in to save

Also known as MRD27, SRY-box 11, CSS9, SRY-box transcription factor 11

Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.

In the Vinony graph

Within Vinony's link graph, SOX11 is referenced by 823 other articles, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.

It sits within the topics Genes on human chromosome 2 and Transcription factors.

Its subject is documented across 5 Wikipedia language editions.

Gene data

SOX11

Name: SRY-box transcription factor 11
Type: protein-coding
Position: 5,692,384–5,701,385 (+)
Aliases: CSS9, IDDMOH, MRD27
Ensembl: ENSG00000176887
RefSeq RNA: NM_003108.4
RefSeq protein: NP_003099.1

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II kidney development lens morphogenesis in camera-type eye lens morphogenesis in camera-type eye outflow tract morphogenesis outflow tract morphogenesis

Molecular function

transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific

Cellular component

chromatin nucleus nucleus nucleus nucleus nucleoplasm

Pathways

Pre-implantation embryo GDNF-RET signaling axis

via MyGene.info

Gene · Ensembl

SRY-box transcription factor 11

Symbol: SOX11
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:5,692,384-5,701,385
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 37733
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/6664
genomic end: 5841516
genomic start: 5692384
chromosome: human chromosome 2
cytogenetic location: 2p25.2
expressed in: medulla oblongata

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections

Contents

Function
Clinical aspect
See also
References
Further reading
External links

Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.

== Function ==

Excerpted from Wikipedia’s “SOX11” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 2 Transcription factors