SPTB
Sign in to saveAlso known as EL3, HS2, HSPTB1, SPH2, spectrin beta, erythrocytic
Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene.
In the Vinony graph
Vinony's link graph records 274 inbound references to SPTB, and connects out to hair keratin, PubMed and human chromosome 14.
It is catalogued under the topic Genes on human chromosome 14.
Vinony links it to 7 Wikipedia language editions.
Gene data
SPTB- Name
- spectrin beta, erythrocytic
- Type
- protein-coding
- Position
- 64,746,283–64,880,019 (−)
- Aliases
- EL3, HS2, HSPTB1, SPH2
- Ensembl
- ENSG00000070182
- RefSeq RNA
- NM_000347.5, NM_001024858.4, NM_001355436.2, NM_001355437.2, XM_011537105.4
- RefSeq protein
- NP_001020029.1, NP_001342365.1, NP_001342366.1, XP_011535407.1, XP_016877101.1
This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
spectrin beta, erythrocytic
- Symbol
- SPTB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:64,746,283-64,880,019
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SPTB PDB 1s35.png
Show 7 more facts
- exact match
- identifiers.org/ncbigene/6710
- HomoloGene ID
- 295
- found in taxon
- Homo sapiens
- genomic end
- 64879907
- genomic start
- 65213002
- chromosome
- human chromosome 14
- cytogenetic location
- 14q23.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene.
== References ==
Excerpted from Wikipedia’s “SPTB” article, available under the CC BY-SA 4.0 licence.