Vitronectin

Protein · UniProt

Vitronectin

Gene

VTN

Organism

Homo sapiens (Human)

Length

478 aa

Molecular mass

54,306 Da

Evidence

1: Evidence at protein level

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway

• Vitronectin.The international journal of biochemistry & cell biology · 1999
• Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier.Neuron · 2022
• Vitronectin and its receptors.Current opinion in cell biology · 1993
• Vitronectin in atherosclerotic disease.Clinica chimica acta; international journal of clinical chemistry · 2006
• Vitronectin--master controller or micromanager?IUBMB life · 2013

via PubMed

• PHASE3UNKNOWN
  An Observer-blind, Cohort Randomized, Exploratory Phase 3 Study to Evaluate the Safety and Immunogenicity of Recombinant Covid-19 Vaccine, mRNA Covid-19 Vaccine and Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine as 4th Dose in Individuals Primed/ Boosted With Various RegimensD'Or Institute for Research and Education · NCT05470803
• PHASE2UNKNOWN
  Immunogenicity and Safety Study of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adultsin ChinaZhejiang Clover Biopharmaceuticals, Inc. · NCT04954131
• PHASE1COMPLETED
  Safety and Immunogenicity Dose-finding Study of Adjuvanted SCB-2020S Vaccine in AdultsClover Biopharmaceuticals AUS Pty · NCT05228314
• PHASE2UNKNOWN
  Efficacy and Safety of JS016 in Patients With SARS-CoV-2 Infection (COVID-19)Peking Union Medical College Hospital · NCT04931238
• PHASE1COMPLETED
  Long-term Follow-up to the Phase 1 Study of Adjuvanted SARS-CoV-2 (SCB 2019) Vaccine for COVID-19.Clover Biopharmaceuticals AUS Pty · NCT04932824
• PHASE1TERMINATED
  CORVax12: SARS-CoV-2 Spike (S) Protein Plasmid DNA Vaccine Trial for COVID-19 (SARS-CoV-2)Providence Health & Services · NCT04627675

via ClinicalTrials.gov

Wikidata facts

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