XK

Also known as Kell blood group precursor, X-linked Kx blood group, KX, MCLDS, NA, NAC, X1k, XKR1

protein-coding gene in the species Homo sapiens

Gene data

Name: X-linked Kx blood group antigen, Kell and VPS13A binding protein
Type: protein-coding
Chromosome: X
Position: 37,685,791–37,732,130 (+)
Aliases: KX, NA, NAC, X1k, XKR1
Ensembl: ENSG00000047597
RefSeq RNA: NM_021083.4, XM_011543978.4, XM_054327716.1
RefSeq protein: NP_066569.1, XP_011542280.1, XP_054183691.1

This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008].