Structure via PubChem · Public domain (PubChem)
adimolol
Sign in to saveAdimolol (developmental code name MEN-935) is antihypertensive agent which acts as a non-selective α1-, α2-, and β-adrenergic receptor antagonist.
In the Vinony graph
Vinony's link graph records 558 inbound references to adimolol, and connects out to propranolol, atenolol and adrenergic receptor.
It sits within the topics Alpha-1 blockers, Alpha-2 blockers and Benzimidazoles.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C25H29N3O3
- Molecular weight
- 419.5 g/mol
- IUPAC name
- 3-[3-[(2-hydroxy-3-naphthalen-1-yloxypropyl)amino]-3-methylbutyl]-1H-benzimidazol-2-one
- SMILES
- CC(C)(CCN1C2=CC=CC=C2NC1=O)NCC(COC3=CC=CC4=CC=CC=C43)O
- InChIKey
- YWRIUGFSIQMHJK-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 73.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 419.221
Show 2 more facts
- chemical formula
- C₂₅H₂₉N₃O₃
- canonical SMILES
- CC(C)(CCN1C2=CC=CC=C2NC1=O)NCC(COC3=CC=CC4=CC=CC=C43)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Adimolol (developmental code name MEN-935) is antihypertensive agent which acts as a non-selective α1-, α2-, and β-adrenergic receptor antagonist.
==Synthesis== The reaction between 1-naphthyl glycidyl ether (1) and 3-(3-amino-3-methylbutyl)-1H-benzimidazol-2-one (2) gives adimolol (3). thumb|left|500px|class=skin-invert-image|Synthesis of adimolol
Excerpted from Wikipedia’s “adimolol” article, available under the CC BY-SA 4.0 licence.