Structure via PubChem · Public domain (PubChem)
azacyclonol
Sign in to saveAzacyclonol (trade names Ataractan, Calmeran, Frenoton, Frenquel, Psychosan), also known as γ-pipradrol, is a drug which is an ataractive; an agent which diminishes hallucinations in psychotic individuals. It has also been called a tranquilizer and antipsychotic, though these definitions are not accurate as it does not actually possess such properties. Despite being a positional isomer of pipradrol, it is not a psychostimulant, and instead has mild depressant effects.
Chemical data
- Formula
- C18H21NO
- Molecular weight
- 267.4 g/mol
- IUPAC name
- diphenyl(piperidin-4-yl)methanol
- SMILES
- C1CNCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O
- InChIKey
- ZMISODWVFHHWNR-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 32.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 267.162
Show 3 more facts
- chemical formula
- C₁₈H₂₁NO
- canonical SMILES
- C1CNCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O
- Commons category
- Azacyclonol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Azacyclonol (trade names Ataractan, Calmeran, Frenoton, Frenquel, Psychosan), also known as γ-pipradrol, is a drug which is an ataractive; an agent which diminishes hallucinations in psychotic individuals. It has also been called a tranquilizer and antipsychotic, though these definitions are not accurate as it does not actually possess such properties. Despite being a positional isomer of pipradrol, it is not a psychostimulant, and instead has mild depressant effects.
The drug was introduced in Europe in the mid-1950s for the treatment of schizophrenia likely because it was found to attenuate the subjective psychedelic effects of LSD and mescaline in humans. However, due to poor and mixed clinical effectiveness, it never gained widespread acceptance and was eventually discontinued.
Excerpted from Wikipedia’s “azacyclonol” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0