BAG1
Sign in to saveAlso known as BAG-1, HAP, RAP46, BCL2 associated athanogene 1, BAG cochaperone 1
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
In the Vinony graph
Within Vinony's link graph, BAG1 is referenced by 19 other articles, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under topics including Ageing, Aging-related genes and Aging-related proteins.
Its subject is documented across 4 Wikipedia language editions.
Gene data
BAG1- Name
- BAG cochaperone 1
- Type
- protein-coding
- Position
- 33,247,820–33,264,720 (−)
- Aliases
- BAG-1, HAP, RAP46
- Ensembl
- ENSG00000107262
- RefSeq RNA
- NM_001172415.2, NM_001349286.2, NM_001349299.2, NM_004323.6
- RefSeq protein
- NP_001165886.1, NP_001336215.1, NP_001336228.1, NP_004314.6
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
BAG cochaperone 1
- Symbol
- BAG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,247,820-33,264,720
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BAG1 PDB 1hx1.png
Show 7 more facts
- HomoloGene ID
- 3190
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/573
- genomic end
- 33264720
- genomic start
- 33247818
- chromosome
- human chromosome 9
- cytogenetic location
- 9p13.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- External links
- Further reading
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
== Function ==
Excerpted from Wikipedia’s “BAG1” article, available under the CC BY-SA 4.0 licence.