BAG1
Sign in to saveAlso known as BAG-1, HAP, RAP46, BCL2 associated athanogene 1, BAG cochaperone 1
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
Gene data
BAG1- Name
- BAG cochaperone 1
- Type
- protein-coding
- Aliases
- BAG-1, HAP, RAP46
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010].
via MyGene.info
Gene · Ensembl
BAG cochaperone 1
- Symbol
- BAG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,247,820-33,264,720
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein BAG1 PDB 1hx1.png
Show 5 more facts
- HomoloGene ID
- 3190
- exact match
- identifiers.org/ncbigene/573
- genomic end
- 33264720
- genomic start
- 33247818
- cytogenetic location
- 9p13.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- External links
- Further reading
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
== Function ==