HBEGF
Sign in to saveAlso known as DTR, DTS, DTSF, HEGFL, heparin binding EGF like growth factor
protein-coding gene in humans that encodes heparin-binding EGF-like growth factor
Gene data
HBEGF- Name
- heparin binding EGF like growth factor
- Type
- protein-coding
- Position
- 140,332,843–140,346,614 (−)
- Aliases
- DTR, DTS, DTSF, HEGFL
- Ensembl
- ENSG00000113070
- RefSeq RNA
- NM_001945.3
- RefSeq protein
- NP_001936.1
Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
signal transductionepidermal growth factor receptor signaling pathwayepidermal growth factor receptor signaling pathwayepidermal growth factor receptor signaling pathwayepidermal growth factor receptor signaling pathwayepidermal growth factor receptor signaling pathwaymuscle organ developmentpositive regulation of cell population proliferation
Molecular function
Pathways
ErbB signaling pathway - Homo sapiens (human)GnRH signaling pathway - Homo sapiens (human)Estrogen signaling pathway - Homo sapiens (human)Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)Proteoglycans in cancer - Homo sapiens (human)Bladder cancer - Homo sapiens (human)Signaling by ERBB2Signaling by ERBB2
via MyGene.info
Gene · Ensembl
heparin binding EGF like growth factor
- Symbol
- HBEGF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:140,332,843-140,346,614
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein HBEGF PDB 1xdt.png
Show 5 more facts
- HomoloGene ID
- 1466
- exact match
- identifiers.org/ncbigene/1839
- genomic end
- 140346603
- genomic start
- 139712428
- cytogenetic location
- 5q31.3
via Wikidata · CC0
Connections
Q180686
Entity
Ensembl genome database project
Entity
FGF8
Gene
Fibroblast growth factor 18
Protein
Wikidata
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gene
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chromosome
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digital object identifier
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insulin
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testosterone
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bibcode
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atherosclerosis
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erythropoietin
Gene
heparin
Entity
human genome
Entity
type 2 diabetes
Disease
glycoprotein
Entity
Q229883
Entity
base pair
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locus
Entity