BRCA2
Also known as breast cancer 2 tumor suppressor, breast and ovarian cancer susceptibility protein 2, mutant BRCA2, Fanconi anemia group D1 protein, BRCA1/BRCA2-containing complex, subunit 2, breast cancer type 2 susceptibility protein, breast and ovarian cancer susceptibility gene, early onset, breast cancer 2, early onset
ludzki gen
Key facts
- Protein family.Symbol
- BRCA2
- Protein family.Name
- BRCA2 repeat
- Protein family.image
- PDB 1n0w EBI.jpg
- Protein family.caption
- crystal structure of a rad51-brca2 brc repeat complex
- Protein family.Pfam
- PF00634
- Protein family.InterPro
- IPR002093
- Protein family.SCOP
- 1n0w
via Wikipedia infobox
Research
10,889 papers- Olaparib for Metastatic Castration-Resistant Prostate Cancer.The New England journal of medicine · 2020
- DNA repair.WormBook : the online review of C. elegans biology · 2006
- Rucaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer Associated with a DNA Damage Repair Gene Alteration: Final Results from the Phase 2 TRITON2 Study.
Article · Polski
BRCA2 – ludzki gen zlokalizowany na chromosomie 13. Germinalne mutacje genu prowadzą, podobnie jak mutacje w BRCA1, do zwiększonego ryzyka raka sutka i jajnika. Białko kodowane przez BRCA2 jest zaangażowane w naprawę DNA (naprawę przez rekombinację uszkodzeń obu nici DNA).
Abstract from DBpedia / Wikipedia · CC BY-SA