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GeneQ5052493· pop 7· linked from 85 articles

CTSW

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Also known as LYPN, cathepsin W

protein-coding gene in the species Homo sapiens

Gene data

CTSW

Name: cathepsin W
Type: protein-coding
Position: 65,879,809–65,883,741 (+)
Aliases: LYPN
Ensembl: ENSG00000172543
RefSeq RNA: NM_001335.4
RefSeq protein: NP_001326.3

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

immune system process proteolysis immune response protein catabolic process

Molecular function

cysteine-type endopeptidase activity cysteine-type peptidase activity cysteine-type peptidase activity

Cellular component

extracellular region extracellular region cytoplasm vacuole endoplasmic reticulum endoplasmic reticulum membrane platelet dense granule lumen

Pathways

Lysosome - Homo sapiens (human)Apoptosis - Homo sapiens (human)Hemostasis Platelet degranulation Platelet activation, signaling and aggregation Response to elevated platelet cytosolic Ca2+

via MyGene.info

Gene · Ensembl

cathepsin W

Symbol: CTSW
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:65,879,809-65,883,741
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Available in 6 languages

via Wikidata sitelinks · CC0