DGCR8

Also known as C22orf12, DGCRK6, Gy1, pasha, Pasha, DGCR8 microprocessor complex subunit, DGCR8, microprocessor complex subunit

protein-coding gene in the species Homo sapiens

In the Vinony graph

Within Vinony's link graph, DGCR8 is referenced by 15 other articles, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.

Vinony files it under DNA repair, Genes on human chromosome 22 and MicroRNA.

Its subject is documented across 10 Wikipedia language editions.

Gene data

DGCR8

Name: DGCR8 microprocessor complex subunit
Type: protein-coding
Position: 20,080,025–20,111,877 (+)
Aliases: C22orf12, DGCRK6, Gy1, pasha
Ensembl: ENSG00000128191
RefSeq RNA: NM_001190326.2, NM_022720.7, XM_006724268.4, XM_047441418.1, XM_047441419.1
RefSeq protein: NP_001177255.1, NP_073557.3, XP_006724331.1, XP_047297374.1, XP_047297375.1

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].