Also known as ECTD1, ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, EDA is referenced by 164 other articles, and connects out to interferon type I, PubMed and X chromosome.
It is catalogued under the topic Genes on human chromosome X.
Its subject is documented across 5 Wikipedia language editions.
Gene data
EDA- Name
- ectodysplasin A
- Type
- protein-coding
- Chromosome
- X
- Position
- 69,616,067–70,039,472 (+)
- Aliases
- ECTD1, ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, HED1
- Ensembl
- ENSG00000158813
- RefSeq RNA
- NM_001005609.2, NM_001005610.4, NM_001005611.1, NM_001005612.3, NM_001005613.4
- RefSeq protein
- NP_001005609.1, NP_001005610.2, NP_001005612.2, NP_001005613.1, NP_001390.1
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ectodysplasin A
- Symbol
- EDA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:69,616,067-70,039,472
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein EDA PDB 1rj7.png
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1896
- chromosome
- human X chromosome
- genomic end
- 70039472
- genomic start
- 68835911
- cytogenetic location
- Xq13.1
- genetic association
- tooth agenesis
via Wikidata · CC0