Also known as FZ-8, hFZ8, frizzled class receptor 8
Frizzled-8 (Fz-8) is a protein that in humans is encoded by the FZD8 gene.
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008].
Biological process
Frizzled-8 (Fz-8) is a protein that in humans is encoded by the FZD8 gene.
== Function ==
via MyGene.info
via Wikidata · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).