Also known as GAN1, KLHL16, gigaxonin, GIG, giant axonal neuropathy gene, GAN gene
Gigaxonin also known as kelch-like protein 16 is a protein that in humans is encoded by the GAN gene.
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008].
Biological process
Gigaxonin also known as kelch-like protein 16 is a protein that in humans is encoded by the GAN gene.
== Function ==
Molecular function
via MyGene.info
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).